Effect of rabbit gastrointestinal stasis (RGIS) on the fecal microbiota of pet rabbits (Oryctolagus cuniculus).

ABSTRACT: Rabbit (Oryctolagus cuniculus) gastrointestinal stasis syndrome (RGIS) is defined as reduced motility of any part of the digestive tract that can lead to impaction and death if left untreated. This study aimed to describe the effect of RGIS on the fecal microbiota of client-owned pet rabbits. Fecal samples from healthy rabbits and rabbits displaying RGIS were obtained and the symptomology of the rabbits was recorded along with any medical intervention. The health outcomes were as follows: 1) Healthy rabbits (Healthy, n = 21), and 2) Rabbits that displayed symptoms of RGIS, were treated, and recovered (RGIS, n = 22). The fecal samples were analyzed using 16S rRNA and 18S rRNA gene amplicon sequencing to characterize the bacterial and eukaryotic microbial communities, respectively. In the 16

SUBMITTER: Rahic-Seggerman FM 

PROVIDER: S-EPMC11856277 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature