Species Identification and Orthologous Allergen Prediction and Expression in the Genus Aspergillus.

ABSTRACT: The genus Aspergillus comprises a diverse group of fungi that can cause a range of health issues, including systemic infections and allergic reactions. In this regard, A. fumigatus has been recognized as the most prevalent allergen-producing species. This genus taxonomic classification has been subject to frequent updates, which has generated considerable difficulties for its classification when traditional identification methodologies are employed. To demonstrate the feasibility of this approach, we sequenced the whole genomes of 81 Aspergillus isolates and evaluated a WGS-based pipeline for precise species identification. This pipeline employed two methodologies: (i) BLASTn web using four barcode genes and (ii) species tree inference by OrthoFinder. Furthermore, we c

SUBMITTER: Zuleta MC 

PROVIDER: S-EPMC11856533 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature