Modulated-Diameter Zirconia Nanotubes for Controlled Drug Release-Bye to the Burst.

ABSTRACT: The performance of an orthopedic procedure depends on several tandem functionalities. Such characteristics include materials' surface properties and subsequent responses. Implant surfaces are typically roughened; this roughness can further be optimized to a specific morphology such as nanotubular roughness (ZrNTs) and the surfaces can further be used as static drug reservoirs. ZrNTs coatings are attracting interest due to their potential to improve the success rate of implant systems, by means of better physical affixation and also micro/nano physio-chemical interaction with the extracellular matrix (ECM). Effective control over the drug release properties from such coatings has been the subject of several published reports. In this study, a novel and simple approach to extending drug rele

SUBMITTER: Onyenso G 

PROVIDER: S-EPMC11856647 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature