The Expression Levels of Heat Shock Protein 90 (HSP90) in Galleria mellonella Following Infection with the Entomopathogenic Nematode Steinernema carpocapsae and Its Symbiotic Bacteria Xenorhabdus nematophila.

ABSTRACT: Heat shock proteins (HSPs), particularly HSP90, play a vital role in insect responses to environmental and biotic stresses by maintaining protein stability and supporting immune defenses. This study explores HSP90 regulation in Galleria mellonella larvae following exposure to the nematode Steinernema carpocapsae and its symbiotic bacterium Xenorhabdus nematophila. Exposure to live nematodes caused slight changes in HSP90 expression, while non-viable nematodes had no effect, suggesting that nematode secretions or symbiotic bacteria do not directly influence HSP90 levels. However, nematodes with altered surface properties significantly increased HSP90 expression. X. nematophila also moderately elevated HSP90 levels but this effect disappeared when weakly bound sur

SUBMITTER: Banfi D 

PROVIDER: S-EPMC11856864 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature