Unveiling the Genomic Features and Biocontrol Potential of Trichoderma hamatum Against Root Rot Pathogens.

ABSTRACT: Fusarium species are among the most significant pathogens causing root rot in Panax notoginseng. In this study, a strain of Trichoderma hamatum was isolated from the rhizosphere soil of P. notoginseng and subjected to whole-genome sequencing. Plate confrontation experiments were conducted to investigate the antagonistic effects of T. hamatum against Fusarium oxysporum, Fusarium solani, and Fusarium acutatum, the primary Fusarium species causing root rot. Whole-genome sequencing revealed 10,774 predicted genes in T. hamatum, of which 454 were associated with carbohydrate-active enzymes (CAZymes) involved in fungal cell wall degradation. Additionally, 11 biosynthetic gene clusters (BGCs) associated with antimicrobial produ

SUBMITTER: Feng Y 

PROVIDER: S-EPMC11856919 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature