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Primary Breast Lymphoma in a Young Female: Non-Hodgkin's Diffuse Large B-Cell Lymphoma in the Presence of Intact Breast Prostheses.


ABSTRACT:

Introduction

Primary breast lymphoma (PBL) is a rare non-Hodgkin lymphoma, predominantly presenting as diffuse large B-cell lymphoma (DLBCL) and primarily affecting the breast, often misdiagnosed due to its nonspecific symptoms resembling breast carcinoma. Breast implants are among the most frequently used medical devices for esthetic and reconstructive purposes.

Case presentation

We present a 24-year-old female with a growing breast mass who was diagnosed with PBL (non-Hodgkin's DLBCL). She underwent successful R-CHOP chemotherapy, resulting in complete remission. Follow-up imaging showed no distant metastasis or significant residual disease, with silicone implants intact and no pathological uptake.

Conclusion

PBL is a rare malignancy that primarily affects postmenop

SUBMITTER: Al-Bitar A 

PROVIDER: S-EPMC11857216 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature