Comparison of Urinary Tract Infection Rates Between Transperineal Prostate Biopsies with and Without Prophylactic Antibiotics: An Updated Systematic Review and Meta-Analysis.

ABSTRACT: Background and Objectives: The European Association of Urology (EAU) Guidelines on Prostate Cancer note emerging evidence suggesting that antibiotic prophylaxis may not be necessary for transperineal prostate biopsies. However, formal recommendations are pending further research. This meta-analysis compares urinary tract infection (UTI) rates following transperineal prostate biopsies with and without antibiotic prophylaxis. Materials and Methods: We searched PubMed, EMBASE, and the Cochrane Library for relevant studies published up until June 2024. The inclusion criteria were as follows: (a) patients undergoing transperineal prostate biopsy; (b) comparisons between groups with and without antibiotic prophylaxis; and (c) outcomes including UTI and sepsis rates. Exclusion crite

SUBMITTER: Cho S 

PROVIDER: S-EPMC11857401 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature