Using In Vitro Models to Study the Interactions Between Environmental Exposures and Human Microbiota.

ABSTRACT: Research has demonstrated a close correlation between human microbiota and overall health, highlighting their intimate connection. Exposure to environmental factors, such as chemical contaminants and biological agents, has the potential to alter the composition and function of microbiota, thereby influencing health outcomes. Meanwhile, microbiota may contribute to host protection by degrading, or rendering harmless, exposures. Environmental exposures demonstrate significant diversity and dynamism; however, conventional methods for exposure-microbiota research, such as animal and epidemiological studies, are often both time-consuming and costly. Additionally, they may raise ethical concerns. This review aimed to examine the existing understanding of employing in vitro models to investigate

SUBMITTER: Cheng Q 

PROVIDER: S-EPMC11857843 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature