The Development and Preparation of Novel Gel Emulsion Systems Based on a Cholesterol Star-Shaped Derivative.

ABSTRACT: Low-molecular-mass gelators (LMMGs) as stabilizers for gel emulsions offer numerous advantages, such as low usage, functionalizability, and insensitivity to phase ratio. Using LMMGs as stabilizers is one of the effective strategies for preparing gel emulsions. Currently, developing LMMGs and stable gel emulsion systems in a rapid and convenient manner remains a challenge. To cope with the challenge, this study aims to develop a simple and efficient gel emulsion preparation method based on LMMGs. In this study, a cholesterol-based star-shaped derivative (CSD) was designed and synthesized as an LMMG. Based on gelation experiments, a high internal phase W/O gel emulsion system (H₂O/CSD-poly(oligo)-dimethylsiloxane/dichloromethane) was successfully developed and stabilized synergist

SUBMITTER: Liu S 

PROVIDER: S-EPMC11857901 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature