Antibacterial and Antibiofilm Activity of Green-Synthesized Zinc Oxide Nanoparticles Against Multidrug-Resistant Escherichia coli Isolated from Retail Fish.

ABSTRACT: Multidrug-resistant (MDR) Escherichia coli is a major foodborne pathogen posing a critical threat to public health, particularly through the contamination of animal products. The increasing prevalence and virulence of MDR E. coli strains underscore the urgent need for alternative antimicrobial strategies. This study aimed to synthesize and characterize zinc oxide nanoparticles (ZnO-NPs) using Stevia rebaudiana as a sustainable capping and reducing agent, aligning with green chemistry principles. Of the 120 fish samples, 74.2% (89/120) were positive for E. coli contamination. Among the identified E. coli strains, 77.8% (119/153) were classified as MDR. Resistance profiling revealed 22 distinct patterns, and seven highly resistant and virulent strains were

SUBMITTER: Elabbasy MT 

PROVIDER: S-EPMC11858201 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature