Molecular Epidemiology of Salmonella enterica Serotype Dublin Isolated from 2011 to 2022 from Veal and Dairy Cattle in Pennsylvania.

ABSTRACT: The emergence of Salmonella enterica serotype Dublin (S. Dublin) presents significant challenges to animal and human health. We analyzed 109 S. Dublin isolates from bovine submissions to the Penn State Animal Diagnostic Laboratory between 2011 and 2022. Using whole genome sequencing, we assessed their phenotypic and genotypic resistance patterns and correlated these traits with case histories and pathology reports. Core-genome analysis identified cgSTs with similar allelic profiles between our isolates and those from the U.S. and Canada, while some cgSTs were unique to our study. Histopathologic findings suggest a predominance of respiratory and gastroenteric/hepatic lesions, aligning with the histopathological case definition for S. Dublin infection. Critically

SUBMITTER: Sekhwal MK 

PROVIDER: S-EPMC11858433 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature