Physico-Chemical Characterization of Amino Acid-Based Deep Eutectic Solvents.

ABSTRACT: Deep eutectic solvents are an exciting class of designer solvents that are increasingly gaining popularity. Deep eutectic solvents based on amino acids are particularly interesting for biomedical applications due to their potential low toxicity. However, very few have been reported to date, and only one of these has been comprehensively studied, made from a combination of proline and glycerol. Here, we report for the first time a systematic investigation into amino acid-based deep eutectic solvents, with a particular focus on the structural features of amino acids that promote eutectic formation and their influence on viscosity, refractive index, surface tension and thermal behavior. Of the 22 amino acids (and related compounds) examined, only 3 (lysine, arginine and, as previously reporte

SUBMITTER: Bryant SJ 

PROVIDER: S-EPMC11858736 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature