Wild-Grown Romanian Eupatorium cannabinum: Advancing Phyto-Nanocarriers via Maltodextrin Micro-Spray Encapsulation-Metabolite Profiling, Antioxidant, Antimicrobial, and Cytotoxicity Insights.

ABSTRACT: In Romanian ethnopharmacology, Eupatorium cannabinum species is known for its remarkable biological activity. We present an advanced approach to encapsulation using maltodextrin matrices to enhance the stability and efficacy of phytoconstituents and nanoparticles. Two distinct carrier systems were developed: (i) a direct micro-spray encapsulation of E. cannabinum in maltodextrin to produce a maltodextrin-encapsulated carrier (MEC), and (ii) a two-step process involving the preparation of a new phytocarrier system based on gold nanoparticles (EC-AuNPs), followed by micro-spray encapsulation in maltodextrin to create the maltodextrin-encapsulated AuNPs system (MEC-AuNPs system). Comprehensive chemical profiling using GC-MS and ESI-QTOF-MS revealed 80 bioactive molecules, includ

SUBMITTER: Vlase G 

PROVIDER: S-EPMC11858835 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature