Central Nervous System Infection by Free-Living Nematode Cephalobus cubaensis in a Human Host in Africa.

ABSTRACT:

Background

Human central nervous system infections due to free-living nematodes, although extremely rare, are usually fatal. Immunodeficiency has not been a feature of most of these cases, unlike the situation pertaining to disseminated Strongyloides stercoralis infection.

Case report

An elderly immunocompetent man presented with a history of tinnitus and otalgia, progressing to central nervous system involvement with confusion, weakness, and other neurological signs. Examination revealed a unilateral external auditory canal soft tissue mass and radiological evidence of ipsilateral temporal bone destruction and brain parenchymal disease. A biopsy of the ear canal mass revealed the presence of an unidentified nematode species, and treatment with anthelminthics was star

SUBMITTER: Sriruttan-Nel C 

PROVIDER: S-EPMC11860163 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature