Chronic Systemic SARS-CoV-2 Infection Without Respiratory Involvement in an Immunocompromised Patient.

ABSTRACT: In a patient on immunosuppressant treatment, SARS-CoV-2 RNA was documented in different extra-respiratory samples over several months in the absence of positive determinations in upper respiratory samples. Whole-genome sequencing of these samples showed the acquisition of different single-nucleotide polymorphisms over time, suggesting viral evolution and thus viral viability.

SUBMITTER: Tejerina F 

PROVIDER: S-EPMC11860550 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature