The Spleen Virome of Australia's Endemic Platypus Is Dominated by Highly Diverse Papillomaviruses.

ABSTRACT: The platypus (Ornithorhynchus anatinus), a unique monotreme, represents a pivotal point in mammalian evolution with its distinctive traits, such as electroreception and venom production. Despite its evolutionary significance, the viral diversity within platypuses remains poorly understood. This study employed next-generation sequencing to investigate the virome of the dead platypuses, uncovering a range of novel and divergent viruses. Among the identified viruses were four complete genomes of papillomaviruses (OaPV1-4) exhibiting substantial divergence from known strains, suggesting a novel genus within the subfamily Secondpapillomavirinae. Additionally, five novel parvoviruses were detected, including two with complete genomes, highlighting the complex viral ecosystem of the

SUBMITTER: Sarker S 

PROVIDER: S-EPMC11860646 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature