Long-term trends in the burden of multiple myeloma in China: a Joinpoint regression and age-period-cohort analysis based on GBD 2021.

ABSTRACT:

Purpose

Multiple myeloma (MM) is a hematologic malignancy originating from plasma cells with clinical manifestations such as hypercalcemia, cytopenias (most commonly anemia) and renal failure. Here, we analyzed the disease burden and changing trends of MM in China from 1990 to 2021, aiming to provide a scientific and effective basis for the prevention and control of MM disease in China.

Methods

We extracted MM related data from the Global Burden of Diseases (GBD) 2021 database from 1990 to 2021. It is described according to incidence, prevalence, mortality, disability-adjusted life years (DALYs), years lived with disability (YLDs), years of life lost (YLLs) and other indicators. Using Joinpoint regression model to analyze the long-term trends of disease burden of MM in China

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11861083 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature