Functional and effective EEG connectivity patterns in Alzheimer's disease and mild cognitive impairment: a systematic review.

ABSTRACT:

Background

Alzheimer's disease (AD) might be best conceptualized as a disconnection syndrome, such that symptoms may be largely attributable to disrupted communication between brain regions, rather than to deterioration within discrete systems. EEG is uniquely capable of directly and non-invasively measuring neural activity with precise temporal resolution; connectivity quantifies the relationships between such signals in different brain regions. EEG research on connectivity in AD and mild cognitive impairment (MCI), often considered a prodromal phase of AD, has produced mixed results and has yet to be synthesized for comprehensive review. Thus, we performed a systematic review of EEG connectivity in MCI and AD participants compared with cognitively healthy older adult controls.

SUBMITTER: Paitel ER 

PROVIDER: S-EPMC11861106 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature