Insight into molecular and mutational scrutiny of epilepsy associated gene Gabrg2 leading to novel computer-aided drug designing.

ABSTRACT: Epilepsy is a neurological disorder that is major cause of disability in the world. This is most severe medical condition related with different ion channel genes, inflammatory molecules depression and stress. For this purpose, precise diagnostic techniques are available. Genetic polymorphisms are major factors behind the occurrence of many disorders therefore they can be valid for diagnostic purpose. This study emphasis the finding of such markers in Lahore population. Epilepsy-causing gene GABRG2 was selected, and the gene was then examined to detect the presence of polymorphic markers with the help of molecular (PCR) and computational analysis. 50 blood samples of epilepsy patients were collected from Children hospital Lahore, out of which 2 samples were shown positive response for GABR

SUBMITTER: Naveed M 

PROVIDER: S-EPMC11861279 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature