Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker-epicardial adipose tissue mass index: a prospective cohort study.

ABSTRACT:

Background

Although reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased. The accumulation of epicardial adipose tissue (EAT) may be associated with poorer STEMI prognosis and could serve as a potential prognostic marker. However, research examining this relationship remains limited.

Methods

This single-center prospective study enrolled 308 STEMI patients. Patients were randomly assigned to training set and validation set in a 7:3 ratio. The primary outcome was MACE one-year post-STEMI. Epicardial adipose tissue mass index (EAMI) was calculated as EAT volume divided by absolute value of the EAT attenuatio

SUBMITTER: Liu Z 

PROVIDER: S-EPMC11861378 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature