Bioaccessibility and Biological Activities of Phytochemicals from Wild Plant Infusions and Decoctions Before and After Simulated In Vitro Digestion.

ABSTRACT: The wild plants Borago officinalis L. (Boraginaceae) and Hypericum perforatum L. (Hypericaceae) are known to have both food and medicinal uses. The aim of the work was to evaluate the bioaccessibility of potentially bioactive phytochemicals in organ-specific infusions and decoctions pre- and post- simulated in vitro oro-gastrointestinal human digestion aiming at both oral intake and topical applications. (Poly)phenols, reducing sugars, and proteins were analysed by spectroscopic and spectrometry techniques (NMR and HPLC-DAD) as well as their antioxidant and antimicrobial activities pre- and post-digestion. As expected, in vitro digestion altered the composition of the extracts. Specifically, the total amount of (poly)phenols as well as the largely correlated antioxidant activity decreased

SUBMITTER: Monari S 

PROVIDER: S-EPMC11861409 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature