Prognostic value of body adipose tissue parameters in cancer patients treated with immune checkpoint inhibitors.

ABSTRACT:

Objective

This study aims to explore the relationship between body adipose tissue characteristics and clinical outcomes in cancer patients receiving immune checkpoint inhibitor (ICI) therapy.

Methods

We conducted an extensive literature search across three major online databases-Embase, PubMed, and the Cochrane Library-to identify studies examining the link between body adipose tissue and treatment outcomes in cancer patients undergoing ICI therapy, from the inception of each database until February 20, 2024. The quality of the included studies was evaluated using the Newcastle-Ottawa Scale. The primary outcomes analyzed were hazard ratios (HRs) for overall survival (OS) and progression-free survival (PFS), as well as odds ratios (ORs) for disease control rate (DCR). Pooled

SUBMITTER: Li Y 

PROVIDER: S-EPMC11861556 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature