Identifying and Linking Patients At Risk for MASLD with Advanced Fibrosis to Care in Primary Care.

ABSTRACT:

Background and aims

Severity of fibrosis is the driver of liver-related outcomes in metabolic dysfunction-associated steatotic liver disease (MASLD), and non-invasive testing such as fibrosis-4 (FIB-4) score is utilized for risk stratification. We aimed to determine if primary care patients at risk for MASLD and advanced fibrosis were evaluated with subsequent testing. A secondary aim was to determine if at-risk patients with normal aminotransferases had advanced fibrosis.

Methods

Primary care patients at increased risk for MASLD with advanced fibrosis (n = 91,914) were identified using previously established criteria. Patients with known alternative/concomitant etiology of liver disease or cirrhosis were excluded. The study cohort included patients with calculated FIB-4 sco

SUBMITTER: Xiao TG 

PROVIDER: S-EPMC11861828 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature