The Humoral Immune Response Against COVID-19 Through Vaccination in Hemodialysis Patients.

ABSTRACT:

Background

This study investigated the humoral responses to SARS-CoV-2 in hemodialysis (HD) patients. The clearance of molecules in the blood during hemodialysis is influenced by factors such as filter pore size, flow rate, operating pressure, and treatment duration. Chronic kidney disease patients often show low antibody titers for pathogens like pneumococcus, influenza virus, and hepatitis B virus.

Methods

In this study, the surrogate virus neutralization test (sVNT) for the wild type (WT) and Omicron variants, as well as spike-specific IgG levels, were measured at two time points (May 2022 and December 2023). Medical records and questionnaires were used to gather participant information.

Results

A total of 26 HD patients were enrolled, including 3 on immunosuppress

SUBMITTER: Park JY 

PROVIDER: S-EPMC11862019 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature