Association of magnesium depletion score with increased stroke incidence and mortality risks in a comprehensive analysis.

ABSTRACT: Stroke is a leading cause of morbidity and mortality worldwide, with modifiable risk factors being crucial for prevention efforts. Magnesium, an essential mineral involved in numerous physiological processes, is linked to cardiovascular health. However, the relationship between magnesium status, assessed through the Magnesium Depletion Score (MDS), and stroke risk remains underexplored. This study aims to investigate the association between MDS and stroke incidence, as well as the potential correlation between MDS and all-cause and cardiovascular disease (CVD) mortality among US adults. Furthermore, we explore the mediation role of Life's Essential 8 (LE8) in the relationship between MDS and stroke. Utilizing data from the National Health and Nutrition Examination Survey (NHANES) from 1999

SUBMITTER: Yuan Z 

PROVIDER: S-EPMC11862158 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature