Lurasidone uses and dosages in Spain: RETROLUR, a real-world retrospective analysis using artificial intelligence.

ABSTRACT:

Introduction

Lurasidone is used for schizophrenia and bipolar depression in many countries, yet there is a lack of existing literature about its use, efficacy, and safety in real life. We aimed to characterize lurasidone-treated patients by analyzing unstructured information in electronic health records (EHRs).

Methods

This was a multicenter, retrospective, observational, and descriptive study that used data extracted from EHRs of patients initiating treatment with lurasidone in four Spanish hospitals from September 2019 to March 2022. Stratification included primary diagnosis, antipsychotic therapy, and lurasidone dose. Natural language processing and machine learning were used to extract and analyze unstructured clinical data using SNOMED CT terminology. Sociodemographic,

SUBMITTER: Mora F 

PROVIDER: S-EPMC11862477 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature