GEPREP: A comprehensive data atlas of RNA-seq-based gene expression profiles of exercise responses.

ABSTRACT:

Background

Physical activity can regulate and affect gene expression in multiple tissues and cells. Recently, with the development of next-generation sequencing, a large number of RNA-sequencing (RNA-seq)-based gene expression profiles about physical activity have been shared in public resources; however, they are poorly curated and underutilized. To tackle this problem, we developed a data atlas of such data through comprehensive data collection, curation, and organization.

Methods

The data atlas, termed gene expression profiles of RNA-seq-based exercise responses (GEPREP), was built on a comprehensive collection of high-quality RNA-seq data on exercise responses. The metadata of each sample were manually curated. Data were uniformly processed and batch effects corrected. A

SUBMITTER: Sun L 

PROVIDER: S-EPMC11863345 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature