Network meta-analysis comparing efficacy of different strategies on medication-overuse headache.

ABSTRACT:

Background

Medication-overuse headache (MOH) is the most common secondary headache disorder, resulting from or leading to the frequent use of acute headache medications. Despite the availability of various treatment strategies, the optimal approach remains uncertain.

Objective

This network meta-analysis (NMA) aimed to evaluate the comparative efficacy of different strategies for managing MOH, focusing on reducing monthly headache days.

Methods

We systematically reviewed randomized controlled trials (RCTs) comparing withdrawal strategies, including bridging therapies, the use of concurrent migraine prevention drugs, and additional education, in adult patients diagnosed with MOH. The primary outcome was the reduction in monthly headache days. Eligible studies were analy

SUBMITTER: Koonalintip P 

PROVIDER: S-EPMC11863719 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature