Liquid biopsy for lung cancer: A cross section on the diagnostic routine experience of a referral Italian institution.

ABSTRACT:

Background

Lung cancer is the leading cause of cancer death worldwide. Over the last decade, molecular testing of a growing number of predictive biomarkers has become mandatory in the management of NSCLC patients. However, a major obstacle in routine clinical practice is the scant quantity of available tissue specimens obtainable from advanced stage of NSCLC patients. Thus, liquid biopsy, mostly involving blood sampling, has now been integrated in routine diagnostic practice. However, although liquid biopsies constitute a versatile, compliant, and dynamic source of nucleic acids, many of the current testing approaches pose few technical challenges. Here, to validate the feasibility of implementing NGS-based liquid biopsy approaches in routine diagnostic practice, we overviewed the

SUBMITTER: de Luca C 

PROVIDER: S-EPMC11863807 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature