Risk factor analysis and predictive model construction of lean MAFLD: a cross-sectional study of a health check-up population in China.

ABSTRACT:

Aim

Cardiovascular disease morbidity and mortality rates are high in patients with metabolic dysfunction-associated fatty liver disease (MAFLD). The objective of this study was to analyze the risk factors and differences between lean MAFLD and overweight MAFLD, and establish and validate a nomogram model for predicting lean MAFLD.

Methods

This retrospective cross-sectional study included 4363 participants who underwent annual health checkup at Yuyao from 2019 to 2022. The study population was stratified into three groups: non-MAFLD, lean MAFLD (defined as the presence of fatty liver changes as determined by ultrasound in individuals with a BMI < 25 kg/m²), and overweight MAFLD (BMI ≥ 25.0 kg/m²). Subsequent modeling analysis was conducted in a populatio

SUBMITTER: Zhu R 

PROVIDER: S-EPMC11863909 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature