Antidepressant activity of flavones from traditional Chinese medicine: a meta-analysis.

ABSTRACT:

Context

Flavones, the key active components in Traditional Chinese Medicine (TCM), have demonstrated antidepressant activity. Given the numerous animal studies conducted, a systematic analysis is essential to provide a valuable reference for future research.

Object

This study investigated the antidepressant activity of flavones based on animal models and summarized the underlying mechanisms.

Methods

We systematically searched 7 bibliographic Databases as of August 12, 2023, such as Web of Science, PubMed, China National Knowledge Infrastructure, etc. The meta-analysis was performed using either the random or fixed-effect model, supplemented by trial sequential analysis (TSA). The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach was

SUBMITTER: Wang Q 

PROVIDER: S-EPMC11864034 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature