Effects of maternal-offspring supplementation of probiotics and synbiotics on the immunity of offspring Bama mini-pigs.

ABSTRACT: Maternal nutrition is one of the main factors regulating the growth and immunity of piglets. This study aimed to investigate the effects of maternal or maternal-offspring supplementation of antibiotics, probiotics, and synbiotics on the immunity of offspring (21, 65, and 125 day-old) in Bama mini-pigs. The results showed that adding antibiotics to maternal diets increased the plasma IFN-γ level of offspring piglets at 21 day-old. Compared with maternal supplementation, maternal-offspring supplementation of antibiotics decreased the IL-10 level in the spleen, probiotics decreased IL-2, IL-10, and TNF-α levels in the ileum, and synbiotics decreased IL-10 and IFN-γ levels in the ileum of offspring piglets. Moreover, maternal-offspring antibiotics supplementation increased the IL-1β level in t

SUBMITTER: Ding S 

PROVIDER: S-EPMC11864950 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature