External validation of the accuracy of cardiovascular risk prediction tools in psoriatic disease: a UK Biobank study.

ABSTRACT:

Introduction

Risk prediction is important for preventing and managing cardiovascular disease (CVD). CVD risk prediction tools designed for the general population may be inaccurate in people with inflammatory diseases.

Objectives

To investigate the performance of four cardiovascular risk prediction tools (QRISK3, Framingham Risk Score, Reynolds Risk Score and SCORE) in psoriatic arthritis (PsA) and psoriasis. We also compare performance in participants with no inflammatory conditions and in people with rheumatoid arthritis (RA).

Methods

This research utilised the UK Biobank Resource. We identified participants with PsA, psoriasis and RA and calculated their cardiovascular risk using each risk tool. We assessed model calibration by comparing observed and predicted outco

SUBMITTER: Hughes DM 

PROVIDER: S-EPMC11865138 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature