Health-related quality-of-life outcomes in CNS WHO grade 2 and 3 meningioma: a systematic review.

ABSTRACT: WHO grade 2 and 3 meningioma constitute approximately 20% of all meningioma. The lower incidence of these more aggressive meningiomas has led to under-representation of clinical outcomes in the literature. It is hypothesised that patients with grade 2 or 3 meningiomas are disabled by tumour and treatment morbidity, contributing to lower health-related quality-of-life (HRQoL). A PRISMA-compliant systematic review was conducted (PROSPERO CRD42023441009). MEDLINE, EMBASE, and Cochrane Library databases were searched between inception and September 2023. Studies of adults (> 16 y.o.) with histologically-proven WHO grade 2 and 3 cranial meningioma who underwent a combination of surgery, radiotherapy, and stereotactic radiosurgery and had HRQoL outcome data were included. Primary outcome was HRQ

SUBMITTER: Cook WH 

PROVIDER: S-EPMC11865157 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature