Comparison of surgical and radiotherapy outcomes in octogenarians with early-stage non-small cell lung cancer: a SEER database retrospective cohort study.

ABSTRACT:

Background

Lung cancer remains the leading cause of death worldwide, yet optimal treatment strategies for octogenarians with early-stage non-small cell lung cancer (NSCLC) remain unclear.

Aims

To investigate treatment patterns and survival outcomes in octogenarians and older with early-stage NSCLC.

Methods

A retrospective cohort study was conducted using Surveillance, Epidemiology, and End Results database. Patients aged ≥ 80 years with stage I-IIA NSCLC diagnosed between 2011 and 2020 were included. Primary treatments included surgery, radiation, and no treatment. Kaplan-Meier curves were used to evaluate overall survival (OS) and cancer-specific survival (CSS) stratified by treatment and year. Propensity score matching balanced clinical characteristics between surge

SUBMITTER: Hua W 

PROVIDER: S-EPMC11865165 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature