Personalized contrast agent dosing to prevent contrast induced nephropathy in high risk populations in Guangdong, China.

ABSTRACT: Contrast-induced nephropathy (CIN) is an acute kidney injury manifests within 72 h post-administration of contrast media, excluding other kidney-damage etiologies. Despite the recognition of CIN, the complex interplay among high-risk factors remains poorly understood, and precision in the existing risk stratification models is lacking. This retrospective, observational cohort study included patients who underwent percutaneous coronary intervention (PCI) or computed tomography angiography (CTA) at four hospitals in Guangdong, China, between 2010 and 2018. Demographic and clinical characteristics of the patients of prognostic interest were collected. The main outcome was CIN occurrence. In total 12,376 patients were included in the final data analysis. Contrast media dosage was positively as

SUBMITTER: Liao M 

PROVIDER: S-EPMC11865306 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature