Economic Evaluation of Total Knee Replacement Compared with Non-Surgical Management for Knee Osteoarthritis in India.

ABSTRACT:

Objective

This study is an economic evaluation of total knee replacement (TKR) in comparison with non-surgical management in India.

Methods

Cost-utility analysis and budget impact analysis (BIA) were conducted on individuals aged ≥ 50 years with osteoarthritis of the knee (OA knee) Kellgren-Lawrence grades 2 and 3 using a provider's perspective. Three scenarios were considered, varying the age at which TKR is administered while assuming a 20-year lifespan for the implant. A Markov model was used to determine incremental cost-effectiveness ratios (ICERs). Sensitivity analysis was conducted incorporating implant costs and other input parameters.

Results

Net quality-adjusted life-years (QALYs) gained per OA knee treated with TKR were superior when performed at the age of

SUBMITTER: Qadeer AS 

PROVIDER: S-EPMC11865410 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature