Diagnostic limitations in advanced stage peripheral arterial disease in a cadaveric study comparing photon-counting and energy-integrating CT detectors.

ABSTRACT: To evaluate the limits of 1st-generation dual-source photon-counting detector CT (PCD-CT) and 3rd-generation dual-source energy-integrating-detector (EID-CT) regarding imaging of advanced stage peripheral arterial disease (ASPAD) of the femoral runoff. One human cadaver with ASPAD of the superficial femoral arteries was surgically prepared to establish continuous extracorporeal perfusion of the right upper leg. In addition to one stent already in place, three more stents were deployed in positions with severe calcification and stenosis to create thirteen different scenarios of ASPAD. CT angiographies with different radiation dose (CTDI_vol 10, 5, 3 mGy) and matching convolution kernels were performed with PCD-CT and EID-CT. In-stent lumen visibility, signal-to-noise ratio (SNR),

SUBMITTER: Hartung V 

PROVIDER: S-EPMC11865436 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature