Proteomic insights into survival strategies of Escherichia coli in perchlorate-rich Martian brines.

ABSTRACT: Brines, potentially formed by the deliquescence and freezing point depression of highly hygroscopic salts, such as perchlorates (ClO₄^-), may allow for the spatial and temporal stability of liquid water on present-day Mars. It is therefore of great interest to explore the microbial habitability of Martian brines, for which our current understanding is, however, still limited. Putative microbes growing in the perchlorate-rich Martian regolith may be harmed due to the induction of various stressors including osmotic, chaotropic, and oxidative stress. We adapted the model organism Escherichia coli to increasing sodium perchlorate concentrations and used a proteomic approach to characterize the adaptive phenotype. Separately, the microbe was adapted to elevated concentrati

SUBMITTER: Kloss LDF 

PROVIDER: S-EPMC11865474 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature