Differences in Treatment Outcomes Depending on the Adjuvant Treatment Modality in Craniopharyngioma.

ABSTRACT:

Purpose

Adjuvant treatment for craniopharyngioma after surgery is controversial. Adjuvant external beam radiation therapy (EBRT) can increase the risk of long-term sequelae. Stereotactic radiosurgery (SRS) is used to reduce treatment-related toxicity. In this study, we compared the treatment outcomes and toxicities of adjuvant therapies for craniopharyngioma.

Materials and methods

We analyzed patients who underwent craniopharyngioma tumor removal between 2000 and 2017. Of the 153 patients, 27 and 20 received adjuvant fractionated EBRT and SRS, respectively. We compared the local control (LC), progression-free survival (PFS), and overall survival between groups that received adjuvant fractionated EBRT, SRS, and surveillance.

Results

The median follow-up period was 77.7

SUBMITTER: Lee BM 

PROVIDER: S-EPMC11865873 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature