Computational analysis of Ayurvedic herbs to explore their potential role as anti-cervical cancer agents.
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ABSTRACT: Cervical cancer is one of the common types of cancer in women. Treatment regimens include use of chemotherapy but it leads to certain side effects thereby creating a need for safer therapeutic options. Ayurveda has a great potential to provide better treatment strategies. In this study, computational approaches have been employed to investigate the molecular mechanism of anti-cervical cancer Ayurvedic herbs. Initially, Ayurvedic plants possessing anti-cervical cancer activities were obtained from literature. Bioactive compounds present in such plants were evaluated for drug-likeliness, biological functions and associations with cancer-related pathways. This resulted in the most promising drug-like bioactive compounds which were found to target cancer pathways like microRNA and proteoglycan
SUBMITTER: Dange S
PROVIDER: S-EPMC11865937 | biostudies-literature | 2025
REPOSITORIES: biostudies-literature
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