Structural Characterization and Antioxidant Properties of a Novel Polysaccharide Isolated from Gymnopetalum cochinchinense.

ABSTRACT: In this investigation, a novel heteropolysaccharide, denoted as PS-HW1, is isolated from Gymnopetalum cochinchinense. The achieved PS-HW1 polymer exhibits a molecular weight of 1.22 × 10² kDa and composes the residues of d-glucose, d-fructose, and d-galactose in a 1:1:2 ratio. The structure of PS-HW1 is elucidated via gas chromatography-mass spectrometry, infrared spectroscopy, and nuclear magnetic resonance spectroscopy, revealing a backbone consisting of (1→4)-d-glucopyranose, (1→4)-d-galactopyranose, and (1→3)-d-fructopyranose residues. Furthermore, PS-HW1 demonstrates remarkable antioxidant activity, with low IC₅₀ values of 0.88 and 3.51 mg·mL^-1 in the DPPH and ABTS assays, respectively. Its total antioxidant capacity is determined to be 0.2672 ±

SUBMITTER: Le TH 

PROVIDER: S-EPMC11865989 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature