Application of multispectral optoacoustic tomography for lower limb musculoskeletal sports injuries in adults.

ABSTRACT: Compositional changes in relation to musculoskeletal injuries are difficult to measure non-invasively. This study aims to use non-invasive label-free imaging with Multispectral Optoacoustic Tomography (MSOT) to evaluate compositional changes with injury. Five different patient groups were examined, covering diagnoses of Achilles or patellar tendinopathy, Achilles tendon rupture and gastrocnemius muscle strain injury. Injured and contralateral limbs were imaged using a commercial MSOT device. Hemoglobin, collagen, and lipid contents were estimated. Some patients were examined before and after exercise. Hemoglobin measures had high reproducibility and displayed systematic changes in response to exercise. The content and exercise response of hemoglobin was equal on both limbs. In contrast, co

SUBMITTER: Svensson RB 

PROVIDER: S-EPMC11866168 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature