BIA-derived muscle indicator thresholds for malnutrition risk prediction in children with β-thalassemia: a cross-sectional study.

ABSTRACT:

Background

Malnutrition is a significant concern in children with β-thalassemia, impacting their growth and overall health. This study aimed to establish optimal thresholds for predicting malnutrition risk in children with β-thalassemia using muscle mass indicators derived from Bioelectrical Impedance Analysis (BIA).

Methods

A cross-sectional study was conducted with 162 pediatric patients diagnosed with β-thalassemia. Nutritional status of them was assessed using the World Health Organization (WHO) Child Growth Standards and references. BIA was performed to obtain fat-free mass (FFM), skeletal muscle mass (SMM), and soft lean mass (SLM). Propensity score matching (PSM) was used to control for age and gender. Receiver Operating Characteristic (ROC) curves were constructed to

SUBMITTER: Zhang L 

PROVIDER: S-EPMC11866567 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature