Childhood respiratory risk profiles associate with lung function and COPD among the old population.

ABSTRACT:

Background

Childhood, often characterized by multiple concurrent risk factors, holds significant influence over long-term respiratory outcomes, with the intricate interplay among these factors representing an intriguing but underexplored avenue for research. We aimed to determine if respiratory risk factors during childhood affect lung function and chronic obstructive pulmonary disease (COPD) in old age.

Methods

Participants were drawn from the Health and Retirement Study cohort. Latent class analysis (LCA) was applied with six variables used to develop the early-life respiratory risk profiles. Linear regressions and logistic regressions were used to assess the associations between childhood respiratory risk profiles and lung function, including peak expiratory flow (PEF) va

SUBMITTER: Qin C 

PROVIDER: S-EPMC11866643 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature