Early-Life Exposures and Odds of Adenomyosis: A Population-Based Case-Control Study.

ABSTRACT:

Background

Adenomyosis can confer life-altering symptoms such as pelvic pain. Yet, the epidemiologic study of this uterine condition lags other gynaecologic conditions. This includes the investigation of intrauterine exposures that could disrupt foetal development and contribute to the presence of adenomyosis in adulthood.

Objective

We investigated nine early-life factors and the odds of adenomyosis using data from a population-based case-control study of enrollees of an integrated healthcare system in Washington State ages 18-59.

Methods

Cases (n = 386) had incident, pathology-confirmed adenomyosis diagnosed between 2001 and 2006. Two control groups were employed: hysterectomy controls (n = 233) and randomly selected age-matched enrollees with an intact uterus ('popu

SUBMITTER: Hall MS 

PROVIDER: S-EPMC11866745 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature