Qnox index for quantification of intraoperative nociception and analgesia: a prospective single-centre validation study.

ABSTRACT:

Background

The Qnox index is a novel monitor to quantify intraoperative nociception based on an electroencephalographic algorithm. We evaluated the ability of the Qnox index to discriminate noxious from non-noxious stimuli, respond to stimuli, and discriminate different levels of analgesia in patients under propofol anaesthesia with neuromuscular block.

Methods

Qnox was compared with heart rate and mean arterial pressure with five designated stimuli: tetanic stimulations without (tetanic 1) and with sufentanil (tetanic 2), skin incision, tracheal intubation, and a non-noxious period. The response around the skin incision was also evaluated at two target remifentanil concentrations.

Results

In 83 adult patients scheduled for elective surgery, Qnox performed worse than

SUBMITTER: Kong H 

PROVIDER: S-EPMC11867073 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature