Placental Vascular Malperfusion in Pregnancies With Congenital Heart Disease: A Prospective Comparative Study.

ABSTRACT:

Background

Advances in congenital heart disease (CHD) management have improved survival rates, resulting in a growing population of women of childbearing age with CHD. These women face higher risk of obstetric and neonatal complications during pregnancy. While the underlying mechanisms remain unclear, previous studies have identified maternal vascular malperfusion (MVM) in their placentas.

Objectives

This study aimed to compare the prevalence of MVM in pregnant women with CHD to those without CHD, assess its association with obstetric and neonatal outcomes, and explore potential risk factors for MVM.

Methods

In this prospective single-center study, we enrolled pregnant women with CHD who were followed from March 2021 to June 2023, along with a control group matched fo

SUBMITTER: Rahnama N 

PROVIDER: S-EPMC11867520 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature