Potentially commercializable nerve guidance conduits for peripheral nerve injury: Past, present, and future.

ABSTRACT: Peripheral nerve injuries are a prevalent global issue that has garnered great concern. Although autografts remain the preferred clinical approach to repair, their efficacy is hampered by factors like donor scarcity. The emergence of nerve guidance conduits as novel tissue engineering tools offers a promising alternative strategy. This review aims to interpret nerve guidance conduits and their commercialization from both clinical and laboratory perspectives. To enhance comprehension of clinical situations, this article provides a comprehensive analysis of the clinical efficacy of nerve conduits approved by the United States Food and Drug Administration. It proposes that the initial six months post-transplantation is a critical window period for evaluating their efficacy. Additionally, this

SUBMITTER: Liu C 

PROVIDER: S-EPMC11867546 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature