Association of a Count of Inpatient Morbidities with 2-Year Outcomes among Infants Born Extremely Preterm.

ABSTRACT:

Objective

To determine if number of neonatal morbidities is associated with death or severe neurodevelopmental impairment (sNDI) among infants born extremely preterm who survived to 36 weeks' postmenstrual age (PMA).

Study design

This is a retrospective cohort analysis of prospectively collected data from 15 NICHD Neonatal Research Network centers. Neonatal morbidities and 2-year outcomes were examined for 3794 infants born at 22 to 26 weeks' gestation from 2014 through 2019 who survived to 36 weeks' PMA.

Results

Serious brain injury (SBI), bronchopulmonary dysplasia (BPD), and severe retinopathy of prematurity (ROP) had the strongest bivariate associations with death or sNDI (ORs, 95% CI): 3.96 (3.39, 4.64), 3.41 (2.94, 3.95), and 2.66 (2.28, 3.11)], respectively. A

SUBMITTER: Dorner RA 

PROVIDER: S-EPMC11867846 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature